Ceporex 500 mg 12 tablets
GlaxoSmithKline
GlaxoSmithKline
Composition
Each film-coated tablet contains
Cephalexin 500 mg.
Excipients: standard tablet formulation (cellulose, magnesium stearate, coating agents).
Product Description
Ceporex is a first-generation cephalosporin antibiotic.
It works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death.
It is active against a broad range of Gram-positive and Gram-negative organisms.
Bactericidal antibiotic.
Effective against staphylococci, streptococci, and some Gram-negative bacteria.
Oral bioavailability allows convenient outpatient treatment.
Indications for Use
Respiratory tract infections: acute and chronic bronchitis, infected bronchiectasis, pneumonia.
Ear, nose, throat infections: otitis media, sinusitis, tonsillitis, pharyngitis.
Urinary tract infections: cystitis, pyelonephritis, prostatitis.
Skin and soft tissue infections: cellulitis, abscesses, wound infections.
Bone infections: osteomyelitis.
Genital infections: gonorrhoea (when penicillin unsuitable), postpartum infections.
Dental infections: adjunct treatment for dental abscesses.
Method of Administration and Dosage
Adults and children >12 years: 1 g twice daily (standard).
Severe infections: up to 1 g three times daily or 3 g twice daily.
Children 1-12 years: 25-60 mg/kg/day in divided doses; severe infections up to 100 mg/kg/day (max 4 g/day).
Children <1 year: dosage individualized by physician.
Duration: continue for at least 2 days after symptoms resolve; chronic infections may require 2 weeks.
Contraindications
Hypersensitivity to cephalexin or other cephalosporins.
History of severe allergic reaction to penicillin.
Precautions
Use with caution in patients with renal impairment.
May interfere with urine glucose tests in diabetics.
Monitor for diarrhoea (risk of Clostridium difficile colitis).
Inform physician before blood tests (may affect results).
Adverse Reactions
Common: diarrhoea, nausea, abdominal pain.
Rare: allergic reactions (rash, urticaria, anaphylaxis), liver enzyme elevations, seizures (high doses in renal impairment).
Serious: pseudomembranous colitis, Stevens-Johnson syndrome (rare).
Pregnancy and Lactation
Generally considered safe; minimal risk during breastfeeding.
Use under medical supervision.
Storage Conditions
Store at room temperature, away from moisture and light.
Packaging
Box containing 12 film-coated tablets (500 mg each).