E Mox 500 mg 16 capsules
Eipico
Eipico
Composition
Amoxicillin (as trihydrate) 500 mg
Description
E-MOX is a penicillin-group antibiotic used to treat bacterial infections of various localizations in adults and children.
Indications for Use
E-MOX is used for the treatment of the following infections
-Acute otitis media
-Acute bacterial sinusitis
-Acute streptococcal tonsillitis and pharyngitis
-Exacerbation of chronic bronchitis
-Community-acquired pneumonia
-Acute cystitis
-Asymptomatic bacteriuria in pregnant women
-Acute pyelonephritis
-Typhoid and paratyphoid fever
-Dental abscess with spreading infection
-Infections of prosthetic joints
-Eradication of Helicobacter pylori
-Lyme disease
-Endocarditis prophylaxis
Dosage and Administration
The dosage of E-MOX depends on the type and severity of the infection, patient’s age, weight, and renal function.
Typical Dosages
-Acute bacterial sinusitis: 250–500 mg every 8 hours or 750 mg – 1 g every 12 hours.
-Acute cystitis: 3 g twice daily for 1 day.
-Acute otitis media: 500 mg every 8 hours.
-Exacerbation of chronic bronchitis: 750 mg – 1 g every 8 hours for 10 days.
-Community-acquired pneumonia: 500 mg – 1 g every 8 hours.
-Lyme disease: 500 mg – 2 g every 8 hours, duration 10–30 days.
-Eradication of Helicobacter pylori: 750 mg – 1 g twice daily in combination with a proton pump inhibitor and another antibiotic (e.g., clarithromycin, metronidazole) for 7 days.
Dose adjustment is required in renal impairment. Detailed information is provided in the package insert.
Contraindications
-Hypersensitivity to amoxicillin, penicillins, or other beta-lactam antibiotics
-History of severe allergic reactions (anaphylaxis, angioedema)
Precautions
-Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS syndrome) may occur.
-High risk of allergic reactions in patients with penicillin hypersensitivity.
-Seizures may occur in renal failure, high doses, or predisposed patients (epilepsy, meningitis).
-Prolonged use may lead to the growth of resistant microorganisms and development of superinfections.
-Use may cause antibiotic-associated diarrhea, including pseudomembranous colitis.
Pregnancy and Lactation
Pregnancy: Use only if the benefits outweigh the potential risks.
Lactation: Amoxicillin is excreted in breast milk and may cause diarrhea and fungal infections in the infant.
Side Effects
Most common
Diarrhea, nausea, skin rash.
Rare and very rare
Leukopenia, thrombocytopenia, anemia.
Anaphylactic reactions, hypersensitivity.
Dizziness, hyperkinesia, seizures.
Hepatitis, elevated liver enzymes.
Pseudomembranous colitis, black hairy tongue.
Interstitial nephritis, crystalluria.
Storage Conditions
Store in a dry place at temperatures not exceeding 25°C.
Packaging
Carton box containing 2 blisters of 8 capsules and a package insert.