ORS 10 sachets
Pharo Pharma
Pharo Pharma
Trade Name
ORS
10 Sachets Oral Rehydration Salt Powder For Oral Solution For prevention and treatment of dehydration
Composition
Sodium chloride, Glucose anhydrous, Potassium chloride, Trisodium citrate dihydrate
Properties
The reconstituted solution contains a mixture of sodium and potassium salts along with glucose, which facilitates the absorption of sodium and potassium from the intestine. Water is drawn from the bowel by the osmotic effect. As well as “drying up” the stools, the dehydration and loss of elec- trolytes caused by the diarrhoea is corrected by the water and electrolytes absorbed.
Indications
Oral rehydration salt is indicated for the treatment of diarrhoea and fluid loss due to diarrhoea in infants, children and adults.
Dosage and administration
Dissolve contents in 1000 ml of boiled, cool water and to be taken orally.
Unused solution should be stored in a refrigerator and discarded 24 hours
after preparation.
Infants
One litre over a period of 24 hours.
1 to 1.5 times their usual feed volume.
Administer with caution to infants.
Children
One litre over 8 to 24 hours, according to age. 250 ml for every loose motion.
Adults
Drink freely as required, or as directed by the physician.
250 ml to 1000 ml of oral rehydration solution for every loose motion has been suggested.
Normal feeding can continue after the initial fluid deficit has been corrected.
Breast feeding should continue between administrations of oral rehydration solution.
Contraindications
cirrhosis of the liver
congestive cardiac failure
nephrotic syndrome
acute and chronic renal failure
ischaemic heart disease
adrenocortical insufficiency
hyperkalemic periodic paralysis
hyperkalemia
hypoventilatory states
chloride depletion due to continuous gastric fluid loss
metabolic or respiratory alkalosis hypocalcemia
hyperosmolar states in anuria or oliguria, • oedematous sodium retaining conditions
hypertension
peripheral or pulmonary oedema or toxaemia of pregnancy
severe vomiting, diarrhoea and dehydration requiring fluid therapy
dextrose malabsorption
in cases of diabetes mellitus
thiamine deficiency
severe under-nutrition
hemodilution
hypophosphatemia
sepsis and trauma
ORS is also contraindicated for use in patients undergoing treatment with the following:
-sodium retaining drugs
-diuretics known to produce hypochloremic alkalosis
Warnings and precautions
Administer with caution in cases of acute dehydration, heat cramps, extensive tissue destruction or if patients are receiving potassium-sparing diuretics.
Concurrent use with other potassium containing drugs may precipitate hyperkalaemia.
It is very important to dissolve Oral Rehydration Salts in water of the correct volume. A weak solution will not contain optimum glucose and electrolyte concentration and a strong solution may give rise to electrolyte imbalance.
Diarrhoea can have very serious consequences in children under 3 years old. Immediate medical advice should be sought. In other age groups, if symptoms persist for more than 24–48 hours, consult a doctor. If nausea and vomiting are present with the diarrhoea, small and frequent amounts of ORS should be taken first. In infants, immediate medical assis-tance should be obtained.
Use within one hour of reconstitution, or within 24 hours if stored in a refrigerator.
Use in patients with pre-eclampsia is contraindicated. The product should only be administered if the expected benefit to the mother is thought to outweigh any possible risk to the foetus or neonate.
Side effects
Common
hypernatraemia, oedema, nausea, vomiting, diarrhoea, abdominal cramps,
thirst, reduced salivation, lachrymation, sweating, fever, tachycardia, renal
failure, respiratory arrest, headache, dizziness, restlessness, irritability,
weakness, muscular twitching, coma, convulsions, hyperkalaemia, gas-
tro-intestinal ulceration, metabolic alkalosis, muscle hypertonicity, flatu-
lence, dehydration and raised blood pressure.
Storage
Store at a temperature not exceeding 30°C In a dry place
Package
Carton box holds 10 sachets and a paper leaflet.