Salofalk 500 mg 20 tablets
Dr. Falk Pharma GmbH
Dr. Falk Pharma GmbH
Composition
Each tablet contains
Mesalazine 500 mg
Properties
Mesalazine inhibits the activity of neutrophilic lipoxygenase and the synthesis of arachidonic acid metabolites (prostaglandins and leukotrienes), which are inflammatory mediators. It inhibits migration, degranulation, phagocytosis of neutrophils, as well as the secretion of immunoglobulins by lymphocytes. Mesalazine has antioxidant properties by binding to free oxygen radicals.
Indications
Ulcerative colitis (treatment of exacerbations and maintenance therapy in remission); Crohn’s disease (mild and moderate forms in the acute phase); rheumatoid arthritis; juvenile rheumatoid arthritis.
Method of administration and dosage
Take 1 tablet 3 times a day after meals.
Contraindications
Porphyria, anemia, severe liver dysfunction, severe renal dysfunction, deficiency of the enzyme glucose-6-phosphate dehydrogenase, children under 5 years of age, lactation period; hypersensitivity to sulfonamides and salicylic acid derivatives.
Precautions
Use with caution in patients with impaired liver and / or kidney function, patients with bronchial asthma, allergic reactions.
During the treatment period, it is recommended to consume an increased amount of liquid.
During the period of treatment, the level of liver enzymes, complete blood count and urine analysis should be monitored.
Side effects
From the nervous system: headache, dizziness, tinnitus, ataxia, convulsions, sleep disturbances, hallucinations, peripheral neuropathy.
From the urinary system: renal dysfunction, interstitial nephritis.
From the digestive system: nausea, vomiting, diarrhea, abdominal pain, anorexia, hepatitis, pancreatitis.
From the respiratory system: interstitial pneumonitis and other lesions of the lung tissue.
From the hematopoietic system: anemia, leukopenia, thrombocytopenia, agranulocytosis.
Reproductive system disorders: transient oligospermia, infertility.
Allergic reactions: skin rash, toxic epidermal necrolysis, malignant exudative erythema, fever, anaphylactic shock.
Others: it is possible to stain yellow skin, urine, soft contact lenses.
Storage method
At a temperature not higher than 30 degrees.
Packaging
The cardboard box holds 20 tablets.