Brimonidine Eye Drops 0.2% 5 ml
Jamjoom Pharmaceuticals
Jamjoom Pharmaceuticals
Composition
Each 1 ml contains
brimonidine tartrate 0.2%
Other ingredients
Sodium chloride
Properties
Brimonidine is a selective alpha2-adrenergic agonist that has a stimulating effect on alpha2-adrenergic receptors. When used in the dosage form of eye drops of 0.15%, the maximum decrease in intraocular pressure (IOP) is achieved after 2 hours. The hypotensive effect of brimonidine is provided by reducing the formation and increasing the outflow of intraocular fluid along the uveoscleral pathway.
Indications
– open-angle glaucoma;
– ophthalmic hypertension (in monotherapy or in combination with other drugs that reduce IOP).
Dosage and administration
Locally. In the conjunctival sac of the affected eye, 1 drop 3 times a day with an interval between injections of about 8 hours.
Brimonidine can be used with other ophthalmic drugs to lower IOP. If you use more than 2 drugs, then you need to take a 5-minute break between them.
Contraindications
– hypersensitivity to brimonidine and other components of the drug;
-simultaneous therapy with MAO inhibitors;
– children’s age up to 2 years, low body weight (up to 20 kg);
– period of breastfeeding.
– orthostatic hypotension, heart failure, cerebrovascular diseases leading to cerebrovascular insufficiency, renal failure (CC below 40 ml / min), liver failure, depression, Raynaud’s syndrome, thromboangiitis obliterans, children under 7 years of age.
Warnings and precautions
Influence on the ability to drive vehicles and mechanisms
Use of Brimonidine may be accompanied by episodes of weakness and drowsiness in some patients. In the event that the patient’s work is associated with potentially hazardous activities, driving vehicles, he must be warned in advance about a possible decrease in the concentration of attention and the speed of psychomotor reactions, and advised to avoid these activities.
Side effects
Organ of vision: very often – allergic conjunctivitis, conjunctival hyperemia, itching of the mucous membrane of the eyes and skin of the eyelids; often – a burning sensation, conjunctival folliculosis or follicular conjunctivitis, local allergic reactions from the eyes (including keratoconjunctivitis), blepharitis, blepharoconjunctivitis, visual impairment, cataracts, conjunctival edema.
Central nervous system: often – headache, drowsiness, insomnia, dizziness.
Cardiovascular system: often – increased blood pressure; infrequently – a decrease in blood pressure.
Respiratory system: often – bronchitis, cough, shortness of breath.
Gastrointestinal tract: often – gastrointestinal disorders – dyspepsia, dryness of the oral mucosa.
Skin and subcutaneous fat: often – a rash.
Infectious and parasitic diseases: often – flu-like syndrome, infectious disease (chills and respiratory infection), rhinitis, sinusitis, (incl. infectious).
Laboratory indicators: often – hypercholesterolemia.
Storage
Store at a temperature not exceeding 30 degrees and use for 30 days after opening.
Package
The cardboard box contains a 5 ml dropper bottle with dropper, insert leaflet.