Orchazid 0.025% eye drops 10 ml
Composition
Each 1 ml drop contains
Ketotifen 0.25 mg,
Benzalkonium chloride 0.1 mg.
Characteristics
Ketotifen belongs to the group of cycloheptathiophenones and has pronounced antihistamine activity.
It is not classified as a bronchodilating anti-asthmatic drug.
Its mechanism of action is associated with inhibition of histamine and other mediator release from mast cells, blocking histamine H1-receptors, and inhibiting the enzyme phosphodiesterase, which leads to an increase in cAMP (cyclic adenosine monophosphate) levels in mast cells.
Indications
Prevention and treatment of acute, subacute, and chronic allergic conjunctivitis and keratoconjunctivitis, seasonal (spring) conjunctivitis, and ocular manifestations of hay fever.
In tablet form, it is used to prevent the development of bronchospasm, asthmatic attacks, and acute allergic reactions, as well as to reduce the dosage and/or discontinue hormonal drugs (glucocorticosteroids) and bronchodilators when used in combination.
Dosage and Administration
For adults and children over 12 years, the eye drops are prescribed as 1 drop into the conjunctival sac of each eye twice daily.
Preventive use in subacute and chronic conditions should begin 3 weeks before contact with the allergen.
Treatment continues throughout the period of allergen exposure.
The duration of eye drop use depends on the type and severity of the disease.
The bottle should be tightly closed after each use.
Contraindications
Hypersensitivity to ketotifen or other components of the preparation; pregnancy and lactation; children under 3 years of age.
Precautions
In cases of acute inflammation or exacerbation of chronic conditions, the drug may be used in combination with corticosteroids.
Patients should be advised of the need for regular use.
Treatment should begin before allergen exposure and continue throughout the allergen period.
The drug should not be used simultaneously with antidiabetic agents.
Soft contact lenses should not be worn during use due to the presence of benzalkonium chloride.
Rigid contact lenses must be removed before instillation and may be reinserted no earlier than 15 minutes after application.
Side Effects
Burning and tingling sensations in the eyes,
blurred vision immediately after instillation.
Irritation of the ocular mucosa,
skin rash around the eyes;
hypersensitivity.
Storage Conditions
Store at a temperature not exceeding 30°C.
Packaging
A 10 ml dropper bottle and a paper insert are contained in a cardboard box.