Vendexine Syrup 125 ml
Eva Pharma
Eva Pharma
Compound
each 5 ml of syrup contains
Dexamethasone 0.5 mg
Chlorpheniramine maleate 2 mg
Properties
Glucocorticosteroid (GCS) – a methylated derivative of fluoroprednisolone, inhibits the release of interleukin-1 and interleukin-2, interferon gamma from lymphocytes and macrophages. It has anti-inflammatory, anti-allergic, desensitizing, anti-shock, anti-toxic and immunosuppressive effects.
Suppresses the release of pituitary adrenocorticotropic hormone (ACTH) and beta-lipotropin, but does not reduce the content of circulating beta-endorphin. It inhibits the secretion of thyroid-stimulating hormone (TSH) and follicle-stimulating hormone (FSH). (chlorpheniramine), has sympathomimetic activity.
Indications
allergic reactions to drugs and foods
Serum sickness, drug exanthema, urticaria, angioedema, allergic rhinitis, hay fever
– diseases that threaten the loss of vision (acute central chorioretinitis, inflammation of the optic nerve)
– allergic conditions (conjunctivitis, uveitis, scleritis, keratitis, iritis)
– systemic immune diseases (sarcoidosis, temporal arteritis)
-proliferative changes in the orbit (endocrine ophthalmopathy, pseudotumors), sympathetic ophthalmia-immunosuppressive therapy in corneal transplantation
– ulcerative colitis, Crohn’s disease, local enteritis.
Dosage and administration
Children 6-12 years old
2.5 ml 3 times a day. The maximum daily dose is 30 ml.
Adults and children over 12 years of age
5 ml every 4-6 hours.
Contraindications
– hypersensitivity to the active substance or auxiliary components of the drug
– peptic ulcer of the stomach and duodenum
-osteoporosis
– acute viral, bacterial and systemic fungal infections (when appropriate therapy is not used)
– Cushing’s syndrome
– severe arterial hypertension
– severe renal insufficiency
– obesity III – IV degree – active form of tuberculosis
– acute psychoses
-pregnancy and lactation
cirrhosis of the liver or chronic hepatitis
-Children up to 2 years old.
Precautionary measures
In diabetes mellitus, tuberculosis, bacterial and amoebic dysentery, arterial hypertension, thromboembolism, heart and kidney failure, ulcerative colitis, diverticulitis, recently formed intestinal anastomosis, Dexamethasone should be used very carefully and subject to the possibility of adequate treatment of the underlying disease. If the patient had a history of psychosis, then treatment with glucocorticosteroids is carried out only for health reasons.
Side effects
Frequent
transient adrenal insufficiency, decreased carbohydrate tolerance, increased appetite and weight gain, mental illness.
Infrequent
hypersensitivity reactions, elevated plasma triglycerides, gastric ulcer, acute inflammation of the pancreas.
Storage method
At a temperature not higher than 30 degrees.
Package
The carton box holds a 125 ml plastic bottle.