Procoralan 7.5 mg 28 tablets
Servier
Servier
Composition
Each tablet contains ivabradine — 7.5 mg.
Excipients: cellulose, stabilizers, coloring agents (per manufacturer’s specification)
Product Description
Procoralan is a cardiovascular medicine containing the active substance ivabradine.
It is used in the treatment of chronic heart failure with reduced ejection fraction, sinus tachycardia, and stable angina pectoris.
Indications for Use
Symptomatic treatment of chronic stable angina in patients with ischemic heart disease and normal sinus rhythm.
Treatment of patients intolerant to or contraindicated for beta‑blockers, or in combination with beta‑blockers when optimal doses do not adequately control symptoms.
Treatment of chronic heart failure (NYHA class II–IV) with systolic dysfunction, sinus rhythm, and heart rate ≥ 75 bpm, in combination with standard therapy including beta‑blockers, or when beta‑blockers are contraindicated or not tolerated.
May be prescribed for hypertension by physician’s decision.
Method of Administration and Dosage
Initial dose: 5 mg twice daily.
Dose may be increased to 7.5 mg twice daily or reduced to 2.5 mg twice daily depending on patient’s heart rate.
In patients over 75 years, a lower starting dose of 2.5 mg twice daily is recommended.
Treatment should be discontinued if heart rate persistently falls below 50 bpm or if bradycardia symptoms occur.
In angina, discontinue therapy if no improvement after 3 months.
Contraindications
Resting heart rate < 70 bpm.
Severe hypotension.
Cardiogenic shock, acute rhythm disorders, acute or unstable heart failure, unstable angina.
Severe liver impairment.
Pregnancy and breastfeeding.
Women of childbearing potential without effective contraception.
Precautions
Use only under medical supervision.
Monitor heart rate and symptoms during therapy.
Adjust dose or discontinue if bradycardia or adverse effects occur.
Adverse Effects
Most common: visual disturbances (“phosphenes” — transient brightness in the visual field).
Possible: cough, diarrhea or constipation, dizziness, erectile dysfunction, nervousness, fatigue, weakness, drowsiness, headache, nausea, vomiting.
Rare: allergic reactions.
Pregnancy and Lactation
Contraindicated.
Use only if prescribed by a physician when no alternatives are available.
Storage Conditions
Store at room temperature (20–25 °C), out of reach of children and pets.
Do not use damaged tablets.
Packaging
Cardboard box containing 4 blisters of 7 tablets each (28 tablets total), with patient information leaflet.