Abilify 15 mg 10 tablets
Otsuka Pharmaceutical
Otsuka Pharmaceutical
Composition
Each tablet contains
Active ingredient: aripiprazole — 15 mg
Description
Antipsychotic medication with partial agonist activity at dopamine and serotonin receptors. Offers a balanced efficacy and tolerability profile for various psychiatric conditions.
Indications for Use
Schizophrenia (adults and adolescents 13–17 years)
Acute manic and mixed episodes in Bipolar I Disorder
Adjunctive treatment of Major Depressive Disorder (adults)
Irritability associated with Autistic Disorder (children 6–17 years)
Tourette’s Disorder (children 6–18 years)
Dosage and Administration
Taken once daily with or without food. Dose depends on indication and age:
Schizophrenia: adults — 10–15 mg/day, adolescents — start at 2 mg, target 10 mg
Bipolar Disorder: adults — 15 mg/day, pediatrics — start at 2 mg, titrate to 10 mg
Depression: start at 2–5 mg/day, up to 15 mg/day
Autism-related irritability: 5–15 mg/day with gradual titration
Tourette’s Disorder: 5–20 mg/day based on weight and response
Dosage adjustment is required with CYP2D6 and CYP3A4 inhibitors/inducers.
Contraindications
Hypersensitivity to aripiprazole
Dementia-related psychosis in elderly
Children under 6 years (based on indication)
Precautions
Increased risk of suicidal thoughts in adolescents
Increased mortality and stroke risk in elderly with dementia
Metabolic changes: hyperglycemia, weight gain
Cardiovascular issues, orthostatic hypotension
Seizures, temperature dysregulation, dysphagia
Side Effects
Common: headache, insomnia, nausea, vomiting, anxiety, drowsiness, dizziness, constipation, weight gain.
In children: somnolence, tremor, extrapyramidal disorder, increased appetite.
Pregnancy and Breastfeeding
Not recommended during pregnancy or lactation. Safety not established.
Storage Conditions
Store below 30°C. Protect from light and moisture.
Packaging
Carton box containing 10 tablets of 15 mg and leaflet.