Dogmatil 50 mg 30 capsules
Sanofi Egypt
Sanofi Egypt
Composition
Each tablet contains
Sulpiride 50 mg
Excipients
Lactose, methylcellulose, talc, magnesium stearate.
Properties
Atypical neuroleptic from the group of substituted benzamides.
Sulpiride has moderate neuroleptic activity in combination with stimulating and thymoanaleptic (antidepressant) action. The neuroleptic effect is associated with antidopaminergic action. In the central nervous system, sulpiride blocks predominantly dopaminergic receptors of the limbic system, and has little effect on the neostriatal system, it has an antipsychotic effect and causes a small number of side effects. The peripheral action of sulpiride is based on the inhibition of presynaptic receptors. An increase in the amount of dopamine in the central nervous system is associated with an improvement in mood, while a decrease is associated with the development of depressive symptoms.
Indications
Neurotic conditions accompanied by inhibition; psychosomatic disorders, including gastric ulcer and duodenal ulcer, ulcerative colitis; acute and chronic psychoses with a predominance of inhibition, agrammatism, abulia; acute and chronic psychoses accompanied by delirium or confusion, including schizophrenia.
Method of administration and dosage
Orally for adults - 100-300 mg / day in 2-3 doses. In children, use a daily dose of 5 mg / kg.
The maximum daily dose for oral administration for adults is 1.6 g.
Contraindications
Pheochromocytoma, arterial hypertension, psychomotor agitation, hypersensitivity to sulpiride.
Precautions
Use with caution in patients with Parkinsonism, elderly people. In severe renal failure, it is recommended to reduce the dose or conduct an intermittent course of treatment.
In patients with epilepsy, before starting therapy, it is necessary to conduct a preliminary clinical and electrophysiological examination, since sulpiride lowers the seizure threshold.
In case of hyperthermia, which is one of the elements of the NMS, sulpiride should be immediately discontinued.
Avoid alcohol consumption during treatment.
Use with caution during pregnancy and lactation and in minimal effective doses.
Use with caution in children.
Side effects
Agitation, dizziness, sleep disorders, dry mouth, heartburn, vomiting, constipation, increased blood pressure, menstrual irregularities, decreased sexual activity. With prolonged use in high doses - galactorrhea, gynecomastia,
allergic reactions.
Storage method
At a temperature not exceeding 30 degrees.
Packaging
A cardboard box contains paper instructions and three blisters, each with 10 tablets.