Diclac 75 mg ID 30 tablets
Sandoz
Sandoz
Composition
Each tablet contains
Diclofenac sodium — 75 mg.
Excipients
lactose monohydrate, calcium hydrogen phosphate dihydrate, corn starch, hydroxypropyl methylcellulose, microcrystalline cellulose, sodium starch glycolate, colloidal silicon dioxide, magnesium stearate, red iron oxide (E172).
Product Description
Nonsteroidal anti‑inflammatory drug (NSAID), derivative of phenylacetic acid.
Exhibits strong anti‑inflammatory, analgesic, and moderate antipyretic effects.
Mechanism: inhibition of cyclooxygenase (COX), reducing prostaglandin synthesis.
Provides peripheral pain relief (via prostaglandin suppression) and central analgesia (via inhibition in CNS and PNS).
Inhibits proteoglycan synthesis in cartilage.
Reduces joint pain, stiffness, and swelling in rheumatic diseases.
Relieves post‑traumatic and postoperative pain and inflammation.
Inhibits platelet aggregation; has desensitizing effect with long‑term use.
Indications for Use
Joint syndromes: rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout.
Degenerative and chronic inflammatory musculoskeletal diseases (osteochondrosis, periarthropathies).
Post‑traumatic inflammation of soft tissues and musculoskeletal system (sprains, contusions).
Back pain, neuralgia, myalgia, arthralgia.
Pain and inflammation after surgery or trauma.
Migraine, dysmenorrhea, adnexitis, proctitis.
Biliary and renal colic.
Pain in ENT infectious‑inflammatory diseases.
Method of Administration and Dosage
Oral use: 1–2 tablets daily.
Maximum daily dose: 150 mg.
Tablets should be taken before meals.
Contraindications
Active erosive/ulcerative GI lesions.
Aspirin triad.
Hematopoietic disorders of unknown origin.
Hypersensitivity to diclofenac or other NSAIDs.
Precautions
Use cautiously in patients with liver, kidney, or GI disease history, dyspepsia, bronchial asthma, hypertension, heart failure, post‑surgery, and elderly patients.
In cases of allergy to NSAIDs or sulfites, diclofenac should be used only in emergencies.
Requires monitoring of liver and kidney function and peripheral blood counts during therapy.
Adverse Reactions / Side Effects
Gastrointestinal: nausea, vomiting, anorexia, epigastric pain, flatulence, constipation, diarrhea; possible erosive/ulcerative lesions, bleeding, perforation; rare liver dysfunction.
CNS: dizziness, headache, agitation, insomnia, irritability, fatigue; rare paresthesia, blurred vision, diplopia, tinnitus, seizures, depression.
Hematologic: rare anemia, leukopenia, thrombocytopenia, agranulocytosis.
Renal: rare dysfunction, edema in predisposed patients.
Dermatologic: rare hair loss.
Allergic: rash, itching, photosensitivity.
Pregnancy and Lactation
Use only if prescribed by a physician, after benefit/risk assessment.
Storage Conditions
Store at temperatures not exceeding 30 °C, in a dry place.
Packaging
Carton box containing 3 blisters of 10 tablets each.