Mark Fast 30 capsules
Marcyrl Pharmaceutical Industries
Marcyrl Pharmaceutical Industries
Composition
Each capsule contains
Chlorzoxazone – 250 mg
Ibuprofen – 200 mg
Description
Mark Fast is a combination medication containing a centrally acting muscle relaxant (Chlorzoxazone) and a non-steroidal anti-inflammatory drug (Ibuprofen). It provides effective relief of muscle pain and spasms associated with trauma, inflammation, or musculoskeletal disorders. It acts by reducing muscle tone and inhibiting prostaglandin synthesis to relieve pain and inflammation.
Indications for Use
Relief of pain and cramping of skeletal muscles in cases of
Sprains and dislocations, Muscle aches, Stiff neck, Tension headaches, Traumatic muscle injury, Back pain, Spondyloarthritis, Cervical syndrome
Dosage and Administration
For oral use, after meals.
Usual dose: 1 to 2 capsules three times daily, according to the severity of the condition.
Contraindications
Hypersensitivity to any component of the product
History of allergic reactions (e.g., bronchospasm) to aspirin or other NSAIDs
Impaired liver function
Porphyria
Precautions
-Use with caution in patients with asthma or nasal polyposis
-Use with caution in patients with clotting disorders or those on anticoagulant therapy
Cardiovascular risk
-NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke
-Risk may increase with duration of use and in patients with cardiovascular disease or risk factors
-Contraindicated for peri-operative pain in coronary artery bypass graft (CABG) surgery
Gastrointestinal risk
-NSAIDs increase the risk of serious gastrointestinal adverse events such as inflammation, bleeding, ulceration, and perforation
-Elderly patients are at higher risk
Hepatotoxicity
-Rare but serious hepatocellular injury reported with chlorzoxazone
-Monitor for early signs of liver toxicity (fever, rash, nausea, vomiting, jaundice, dark urine, etc.)
-Discontinue if liver enzymes or bilirubin are elevated
-Avoid concomitant use with alcohol or CNS depressants due to additive effects
Side Effects
Most common
Nausea
Epigastric pain
Heartburn
Diarrhea
Vomiting
Indigestion
Constipation
Flatulence
Rare
Peptic ulcer
Gastrointestinal bleeding
Pancreatitis
Gastritis
Hepatitis
Jaundice
Abnormal liver function tests
Stevens-Johnson syndrome
Pregnancy and Lactation
The safety of Mark Fast during pregnancy is not adequately studied
The drug may be excreted in breast milk and affect a nursing infant
Use only under medical supervision during pregnancy or lactation
Storage Conditions
Store in a dry place at a temperature not exceeding 30°C.
Packaging
Carton box containing 3 blister strips, each containing 10 hard gelatin capsules, a package insert.