Solpadol 5 mg 6 tablets
Global napi pharmaceuticals
Global napi pharmaceuticals
Composition
Each tablet contains
Zolmitriptan 5 mg.
Inactive ingredients
Mannitol, Avicel, Aspartame, Starch, Aerosil, Magnesium Stearate.
Properties
Zolmitriptan causes vasoconstriction in intracranial blood vessels (including arteriovenous anastomoses) and sensory endings of the trigeminal nerve and release of anti-inflammatory neuropeptides.
Indications
Treatment of acute migraine with or without aura in adults.
Dosage and administration
The initial dose is 2.5 mg or less.
The dose may be repeated after 2 hours if symptoms persist. The maximum dose is 10 mg per day. Zolmitriptan is taken with or without food.
Contraindications
hypersensitivity to zolmitriptan. Ischemic heart disease, spasm of the coronary arteries.
Uncontrolled arterial hypertension, previous cerebrovascular accident or transient ischemic attack.
Side effects
Spasm of the coronary arteries, increased appetite. Impaired liver function and thirst.
Rare were anorexia, constipation.
Drowsiness, paresthesia, myalgia, muscle weakness, fatigue.
Palpitations, angina pectoris, headache, urticaria.
Drug interaction
antidepressants increase the toxicity of triptans to the CNS. The combination with ergot alkaloids increases the risk of developing vasospasm. Cimetidine inhibits the metabolism of zolmitriptan.
Pregnancy and lactation
safe use during pregnancy and lactation has not been established.
Warnings and precautions
Recommended as monotherapy and should not be taken concomitantly with other treatments for acute migraine.
The drug should be used only when a clear diagnosis of migraine has been established. Feelings of tightness, pain, pressure and heaviness in the atrium, throat, neck and jaw were noted after treatment with Solpadol tablets. Patients who experience signs or symptoms indicative of angina pectoris and patients who experience other symptoms or signs indicative of decreased arterial blood flow, such as ischemic bowel syndrome or Raynaud’s syndrome, should be monitored by ECG if dosing is resumed and similar symptoms recur.
With caution prescribed for patients with impaired liver function, with epilepsy or convulsions.
This drug is intended to relieve a migraine attack, not to prevent or reduce the number of attacks.
Storage
Store at a temperature not exceeding 30°C, protected from light and out of reach of children.
Package
The box contains 3 blisters of 2 tablets, paper leaflet.