Cetafen Plus N 30 tablets
Aspin Pharma
Aspin Pharma
Ingredients
Ibuprofen 200 mg
Paracetamol 500 mg
Caffeine 65 mg.
Description
A combination analgesic-antipyretic for symptomatic relief of pain and fever. Ibuprofen reduces inflammation and pain, paracetamol provides analgesia and antipyresis, caffeine enhances analgesic effects and reduces drowsiness. Intended for short-term use in adults.
Indications
Headache (including migraine), toothache, backache, rheumatic pain.
Dysmenorrhea (painful menstruation).
Cold and flu symptoms (fever, sore throat, body aches).
Neuralgia, myalgia.
Dosage and Administration
Adults (over 18): 1 tablet up to 3 times daily after meals.
Max dose: Not more than 2 tablets per dose and 6 tablets per day.
Interval: At least 6 hours between doses.
Duration: Not more than 3–5 days without medical advice.
Contraindications
- Hypersensitivity to ibuprofen, paracetamol, caffeine, or excipients.
- Asthma, urticaria, or allergic reactions to NSAIDs (aspirin, ibuprofen).
- Peptic ulcer disease, GI bleeding or perforation.
- Severe heart failure (NYHA Class IV), renal or hepatic failure.
- Third trimester of pregnancy, lactation, children under 18 years.
Precautions
- Paracetamol overdose: Do not combine with other paracetamol-containing products. Risk of severe liver damage.
- GI risk: Use cautiously in elderly, patients with ulcer history, or those taking corticosteroids/anticoagulants.
- Cardiovascular risk: Avoid prolonged use in hypertension, CVD.
- Caffeine: Limit coffee, tea, energy drinks to avoid caffeine overdose.
- Liver/kidney: Caution in mild to moderate impairment.
Adverse Reactions
- GI: Nausea, abdominal pain, heartburn, ulcers, bleeding.
- Allergic: Skin rash, bronchospasm, anaphylaxis.
- Liver: Elevated liver enzymes, hepatotoxicity (overdose).
- Other: Dizziness, tachycardia, insomnia (due to caffeine).
Pregnancy and Lactation
Pregnancy: Contraindicated in third trimester. In first–second trimesters, use only if benefits outweigh risks.
Lactation: Caffeine excreted in breast milk. Not recommended.
Storage
Store below 30°C in a dry place.
Package
Carton box with 3 blisters (10 tablets each) + leaflet.