Itomash 50 mg
Mash Premiere for Pharmaceutical Industries
Mash Premiere for Pharmaceutical Industries
Trade Name
Itomash 50 mg
Composition
Itopride hydrochloride 50 mg
Inactive ingredients
Hydroxypropyl Methyl cellulose
Hydroxyethyl cellulose
Properties
Itopride hydrochloride activates gastrointestinal propulsive motility due to its dopamine D2 antagonizing activity and acetylcholinesterase inhibitory activity. Itopride hydrochloride activates acetylcholine release and inhibits its degradation.
Indication
Itopride hydrochloride is used in the treatment of gastrointestinal symptoms of:
-Functional dyspepsia
-Non-ulcer dyspepsia (chronic gastritis)
-sensation of bloating
-early satiety
-upper abdominal pain or discomfort
-anorexia
-heartburn
-nausea and vomiting
Dosage and administration
The recommended dose of Itomash for adult patients is 150 mg daily (one tablet 50 mg taken three times a day before meals). The dose may be reduced according to a patient’s age and symptoms.
Contraindication
Itopride hydrochloride is contraindicated in patients with known hypersensitivity to itopride hydrochloride or any of the excipients. It should not be used in patients in whom an increase in gastrointestinal motility could be harmful e.g. hemorrhage, mechanical obstruction or perforation.
Side effects
Blood and lymphatic system disorders
Leucopenia, thrombocytopenia
Immune system disorders
Anaphylactoid reactions
Endocrine disorders
Increased prolactin level and gynecomastia
Nervous system disorders
Dizziness, headache and tremor
Gastrointestinal disorders
Diarrhea, constipation, abdominal pain, increased saliva and nausea
Hepato-biliary disorders
Jaundice
Skin and subcutaneous tissue disorders
Rash, redness and itching
Warnings and precautions
Itomash enhances the action of acetylcholine and may produce cholinergic side effects.
Storage
Store at a temperature not exceeding 30°C in a dry place.
Package
The carton box holds 3 strips each of 10 tablets and inner leaflet.