Primperan 10mg / 2ml 12 ampoules
Sanofi Egypt
Sanofi Egypt
Tradename
Primperan
Primperan
Composition
Each ampoule contains
Metoclopramide hydrochloride 10.00 mg
Auxiliary components
Sodium chloride, water for injection.
Properties
Antiemetic. A specific blocker of dopamine (D2) and serotonin (5-NTZ) receptors, inhibits the chemoreceptors of the trigger zone of the brain stem, weakens the sensitivity of the visceral nerves that transmit impulses from the pylorus of the stomach and duodenum to the vomiting center.
Indications
– vomiting, nausea, hiccups of various origins (in some cases, it can be effective in vomiting caused by radiation therapy or taking cytostatics);
– atony and hypotension of the stomach and intestines (in particular, postoperative);
-dyskinesia of the biliary tract in the hypomotor type;
-reflux esophagitis;
-flatulence;
– functional pyloric stenosis;
– as part of the complex therapy of exacerbations of gastric ulcer and duodenal ulcer;
– it is used to enhance peristalsis during X-ray contrast studies of the gastrointestinal tract;
– as a means of facilitating duodenal intubation (to accelerate gastric emptying and the movement of food through the small intestine).
Method of administration and dosage
Recommended dose for children from 1 to 18 years old
0.1 mg-0.15 mg / per 1 kg of the child’s weight 1-2 times a day.
Adults
10 mg 3 times a day.
The maximum daily dose is 0.5 mg / kg.
The maximum course of treatment is 5 days.
Contraindications
– bleeding from the gastrointestinal tract;
– stenosis of the pylorus of the stomach;
-mechanical intestinal obstruction;
-perforation of the wall of the stomach or intestines;
-pheochromocytoma;
-epilepsy;
-glaucoma;
– extrapyramidal disorders;
-Parkinson’s disease;
-prolactin-dependent tumors;
-vomiting during treatment or overdose with antipsychotics and in patients with breast cancer;
– bronchial asthma in patients with hypersensitivity to sulfites;
-pregnancy (I trimester);
– lactation period;
– early childhood;
– hypersensitivity to metoclopramide or any of the components of the drug.
Precautionary measures
Not effective for vomiting of vestibular origin.
During the period of drug treatment, alcohol consumption is not recommended.
Influence on the ability to drive vehicles and mechanisms
It is recommended to be careful when driving a vehicle or when working with potentially dangerous mechanisms that require increased concentration of attention and speed of psychomotor reactions.
Side effects
From the nervous system: extrapyramidal disorders – spasm of the facial muscles, trismus, rhythmic protrusion of the tongue, bulbar type of speech.
From the digestive system: constipation or diarrhea, rarely – dry mouth.
From the side of the cardiovascular system: atrioventricular block.
From the side of metabolism: porphyria.
Allergic reactions: urticaria, bronchospasm, angioedema.
Storage method
Store at a temperature not exceeding 25 degrees.
Package
The cardboard box holds 12 ampoules and paper instructions.