Protofix 40 mg 14 tablets
Rameda Pharmaceutical Company
Rameda Pharmaceutical Company
Composition (per 1 tablet)
• Pantoprazole — 40 mg.
Protofix 40 mg is a proton pump inhibitor (PPI) used to treat gastrointestinal diseases associated with increased acidity. It provides sustained reduction of gastric acid secretion.
Pharmacological properties
• Pantoprazole blocks the H⁺/K⁺-ATPase enzyme in the parietal cells of the stomach
• Suppresses both basal and stimulated acid secretion
• Effect begins within 1–2 hours and lasts up to 24 hours.
Indications
• Erosive and ulcerative reflux esophagitis
• Severe forms of gastroesophageal reflux disease (GERD)
• Peptic ulcer disease of the stomach and duodenum
• Zollinger–Ellison syndrome and other hypersecretory conditions
• Maintenance therapy in patients with frequent GERD relapses.
Dosage and administration
Pantoprazole dosage for adults
Gastroesophageal reflux disease (GERD)
Usually prescribed 40 mg orally once daily.
Treatment duration is 8 to 16 weeks depending on symptom severity and response.
Erosive esophagitis
Initial dose is 40 mg orally once daily for 8–16 weeks.
Maintenance therapy with the same 40 mg once daily dose may be used long-term after remission.
Zollinger–Ellison syndrome and other hypersecretory conditions:
Recommended initial dose is 40 mg orally once daily.
Dose may be increased if necessary; maximum daily dose is 240 mg.
Gastric ulcer (off-label use)
40 mg orally once daily for 4 weeks.
Duodenal ulcer disease (off-label use)
40 mg once daily for 2 weeks, with possible extension if needed.
Dosage for children
Used in children aged 5 years and older.
• Body weight 15–39 kg: 20 mg pantoprazole once daily. Treatment duration up to 8 weeks.
• Body weight 40 kg and above: 40 mg once daily. Treatment duration up to 8 weeks.