Tobradex Ophthalmic Ointment 3.5 g
Composition
Tobramycin 0.3% w/w,
dexamethasone 0.1% w/w.
Other Ingredients
Chlorobutanol, mineral oil, petrolatum base.
Product Description
A combined ophthalmic preparation containing dexamethasone, a corticosteroid that blocks inflammatory mediators, and tobramycin, an aminoglycoside antibiotic that inhibits bacterial growth.
Together they provide anti‑inflammatory and antibacterial effects for the treatment of eye conditions.
Indications for Use
Inflammatory eye diseases with actual or potential bacterial infection.
Chronic inflammation of the uveal tract.
Eye injuries caused by chemical, radiation, or thermal burns.
Eye injuries due to foreign bodies.
Effective only against bacterial infections (not viral or fungal).
Method of Administration and Dosage
Adults: Apply a ribbon of ointment about 1.5 cm into the conjunctival sac of the affected eye(s) 3–4 times daily.
May be combined with Tobradex suspension (e.g., at bedtime).
When using other ophthalmic preparations, allow at least 5 minutes between applications; ointments should be applied last.
In case of overdose, rinse with warm water.
Do not double the dose if one is missed.
Contraindications
Hypersensitivity to tobramycin, dexamethasone, or other components.
Allergy to aminoglycoside antibiotics.
Herpes simplex keratitis.
Varicella or other viral eye infections.
Fungal or parasitic eye infections.
Mycobacterial eye infections, including tuberculosis.
Active untreated eye infections.
Precautions
Not tested in children under 18 years.
Long‑term use increases risk of glaucoma, cataract, elevated intraocular pressure, and infections.
Regular monitoring of intraocular pressure is required during prolonged therapy.
Contact lens use is not recommended during treatment.
Caution in patients with myasthenia gravis, Parkinson’s disease, or diabetes.
Inform physician about concomitant medications (NSAIDs, antivirals, HIV treatments such as ritonavir or cobicistat).
Vision may be blurred immediately after application; avoid driving or operating machinery until vision clears.
Keep out of reach of children.
Adverse Reactions / Side Effects
Common: eyelid redness or swelling, tearing, dry eyes, ocular allergy, irritation, pain, itching, blurred vision, headache, nausea, metallic taste, skin rash, eyelid drooping.
Rare: severe allergic reactions (facial swelling, difficulty breathing, hives, erythema multiforme, blisters), increased intraocular pressure, glaucoma, cataract, serious vision problems.
Pregnancy and Lactation
Use only under medical supervision.
Storage Conditions
Store at temperatures not exceeding 25 °C, in a dry place, away from direct sunlight.
Packaging
Cardboard box containing a 3.5 g tube and leaflet.