Neozolid 600 mg 3 tablets
Borg Pharmaceutical
Borg Pharmaceutical
Compound
Each tablet contains
azithromycin (as dihydrate) 600 mg
Auxiliary components
Calcium phosphate dibasic dihydrate, croscarmellose sodium, magnesium stearate, aerosil 200, sodium saccharin.
Properties
An antibiotic of the macrolide group, is a representative of azalides. It has a wide spectrum of antimicrobial activity. The mechanism of action of azithromycin is associated with the suppression of protein synthesis of microbial cells. By binding to the 50S subunit of ribosomes, it inhibits the peptide translocase at the translation stage, inhibits protein synthesis, and slows down the growth and reproduction of bacteria. Acts bacteriostatically. In high concentrations, it has a bactericidal effect.
It has activity against a number of gram-positive, gram-negative, anaerobic, intracellular and other microorganisms.
Indications
Infectious and inflammatory diseases caused by microorganisms sensitive to azithromycin: infections of the upper respiratory tract and upper respiratory tract (tonsillitis, sinusitis, tonsillitis, pharyngitis, otitis media); infections of the lower respiratory tract (acute bronchitis, exacerbation of chronic bronchitis, pneumonia, including those caused by atypical pathogens); infections of the skin and soft tissues (acne vulgaris of moderate severity, erysipelas, impetigo, secondarily infected dermatoses); uncomplicated urinary tract infections caused by Chlamydia trachomatis (urethritis and / or cervicitis); the initial stage of Lyme disease (borreliosis) is migratory erythema (erythema migrans).
Dosage and administration
The optimal dosage regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.
The drug is taken orally 1 time / day 1 hour before or 2 hours after a meal, without chewing.
Contraindications
Hypersensitivity to azithromycin, erythromycin, other macrolides or ketolides; hypersensitivity to the excipients of the drug used; severe liver dysfunction; severe renal dysfunction (CC <40 ml / min); simultaneous use with ergotamine and dihydroergotamine.
Precautionary measures
Caution should be used in patients with mild to moderate hepatic impairment due to the possibility of developing fulminant hepatitis and severe hepatic failure. In the presence of symptoms of impaired liver function, such as rapidly increasing asthenia, jaundice, dark urine, bleeding tendency, hepatic encephalopathy, azithromycin therapy should be discontinued and a study of the functional state of the liver should be carried out.
For mild to moderate renal impairment (CC> 40 ml / min), azithromycin therapy should be carried out with caution under the control of the state of renal function.
Side effects
From the nervous system: often – headache; infrequently – dizziness, taste disturbance, paresthesia, drowsiness, insomnia, nervousness.
From the digestive system: very often – diarrhea; often – nausea, vomiting, abdominal pain.
Laboratory data: often – a decrease in the number of lymphocytes, an increase in the number of eosinophils.
Storage method
Store at a temperature not exceeding 30 degrees.
Package
The cardboard box contains a blister of 3 tablets, paper instructions.